Serveur d'exploration sur le lymphœdème

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Postmastectomy Lymphedema

Identifieur interne : 007887 ( Main/Exploration ); précédent : 007886; suivant : 007888

Postmastectomy Lymphedema

Auteurs : Corinne Becker ; Jalal Assouad ; Marc Riquet ; Geneviève Hidden

Source :

RBID : PMC:1448940

Descripteurs français

English descriptors

Abstract

Background and Objectives:

Lymphedema complicating breast cancer treatment remains a challenging problem. The purpose of this study was to analyze the long-term results following microsurgical lymph node (LN) transplantation.

Methods:

Twenty-four female patients with lymphedema for more than 5 years underwent LN transplantation. They were treated by physiotherapy and resistant to it. LNs were harvested in the femoral region, transferred to the axillary region, and transplanted by microsurgical procedures. Long-term results were evaluated according to skin elasticity, decrease, or disappearance of lymphedema assessed by measurements, isotopic lymphangiography, and ability to stop physiotherapy.

Results:

The postoperative period was uneventful; skin infectious diseases disappeared in all patients. Upper limb perimeter returned to normal in 10 cases, decreased in 12 cases, and remained unchanged in 2 cases. Five of 16 (31%) isotopic lymphoscintigraphies demonstrated activity of the transplanted nodes. Physiotherapy was discontinued in 15 patients (62.5%). Ten patients were considered as cured, important improvement was noted in 12 patients, and only 2 patients were not improved.

Conclusion:

LN transplantation is a safe procedure permitting good long-term results, disappearance, or a noteworthy improvement, in postmastectomy lymphedema, especially in the early stages of the disease.


Url:
DOI: 10.1097/01.sla.0000201258.10304.16
PubMed: 16495693
PubMed Central: 1448940


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Axilla</term>
<term>Breast Neoplasms (surgery)</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymph Nodes (transplantation)</term>
<term>Lymphedema (diagnostic imaging)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (surgery)</term>
<term>Lymphography</term>
<term>Mastectomy (adverse effects)</term>
<term>Microsurgery (methods)</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
<term>Time Factors</term>
<term>Treatment Outcome</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aisselle</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (imagerie diagnostique)</term>
<term>Lymphoedème (étiologie)</term>
<term>Lymphographie</term>
<term>Mastectomie (effets indésirables)</term>
<term>Microchirurgie ()</term>
<term>Noeuds lymphatiques (transplantation)</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tumeurs du sein ()</term>
<term>Études de suivi</term>
<term>Études rétrospectives</term>
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<term>Mastectomy</term>
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<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr">
<term>Mastectomie</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr">
<term>Lymphoedème</term>
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<term>Microsurgery</term>
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<term>Breast Neoplasms</term>
<term>Lymphedema</term>
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<term>Lymph Nodes</term>
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<term>Lymphoedème</term>
<term>Noeuds lymphatiques</term>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Axilla</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymphography</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
<term>Time Factors</term>
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<term>Adulte d'âge moyen</term>
<term>Aisselle</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Lymphographie</term>
<term>Microchirurgie</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
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<term>Études de suivi</term>
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<front>
<div type="abstract" xml:lang="en">
<sec>
<title>Background and Objectives:</title>
<p>Lymphedema complicating breast cancer treatment remains a challenging problem. The purpose of this study was to analyze the long-term results following microsurgical lymph node (LN) transplantation.</p>
</sec>
<sec>
<title>Methods:</title>
<p>Twenty-four female patients with lymphedema for more than 5 years underwent LN transplantation. They were treated by physiotherapy and resistant to it. LNs were harvested in the femoral region, transferred to the axillary region, and transplanted by microsurgical procedures. Long-term results were evaluated according to skin elasticity, decrease, or disappearance of lymphedema assessed by measurements, isotopic lymphangiography, and ability to stop physiotherapy.</p>
</sec>
<sec>
<title>Results:</title>
<p>The postoperative period was uneventful; skin infectious diseases disappeared in all patients. Upper limb perimeter returned to normal in 10 cases, decreased in 12 cases, and remained unchanged in 2 cases. Five of 16 (31%) isotopic lymphoscintigraphies demonstrated activity of the transplanted nodes. Physiotherapy was discontinued in 15 patients (62.5%). Ten patients were considered as cured, important improvement was noted in 12 patients, and only 2 patients were not improved.</p>
</sec>
<sec>
<title>Conclusion:</title>
<p>LN transplantation is a safe procedure permitting good long-term results, disappearance, or a noteworthy improvement, in postmastectomy lymphedema, especially in the early stages of the disease.</p>
</sec>
</div>
</front>
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